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Symbol
Name
ID

Slc6a5
solute carrier family 6 (neurotransmitter transporter, glycine), member 5
MGI:105090

Phenotype annotations related to nervous system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Exaggerated startle response	Myoclonus	Brisk reflexes	Global developmental delay	Bilateral tonic-clonic seizure
Disease(s) Associated with SLC6A5
hyperekplexia 3

Mouse Phenotypes		nervous system phenotype	tonic seizures	abnormal neuromuscular synapse morphology	abnormal neuron physiology	abnormal CNS synaptic transmission	abnormal inhibitory postsynaptic currents	abnormal miniature inhibitory postsynaptic currents	decreased miniature inhibitory postsynaptic current amplitude	decreased miniature inhibitory postsynaptic current frequency
Availability	Mouse Genotype	nervous system phenotype	tonic seizures	abnormal neuromuscular synapse morphology	abnormal neuron physiology	abnormal CNS synaptic transmission	abnormal inhibitory postsynaptic currents	abnormal miniature inhibitory postsynaptic currents
	Slc6a5^m1J/Slc6a5^m1J
	Slc6a5^tm1Betz/Slc6a5^tm1Betz	*
	Slc6a5^trsl/Slc6a5^trsl

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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